(2R)-3-hydroxy-1-methoxy-1-oxopropan-2-aminium chloride
DL-Serine methyl ester hydrochloride
CAS: 5619-04-5
Molecular Formula: C4H10ClNO3
(2R)-3-hydroxy-1-methoxy-1-oxopropan-2-aminium chloride - Names and Identifiers
| Name | DL-Serine methyl ester hydrochloride |
| Synonyms | methyl serinate H-DL-SER-OME HCL H-DL-Ser-OMe·HCl DL-SERINE-OME HCL TIMTEC-BB SBB004026 DL-serine methyl ester hcl Methyl-dl-serine hydrochloride methyl L-serinate hydrochloride DL-SERINE METHYL ESTER HYDROCHLORIDE DL-Serine methyl ester hydrochloride (2R)-3-hydroxy-1-methoxy-1-oxopropan-2-aminium 3-hydroxy-1-methoxy-1-oxopropan-2-aminium chloride (2R)-3-hydroxy-1-methoxy-1-oxopropan-2-aminium chloride (RS)-2-Amino-3-hydroxypropionic acid methyl ester hydrochloride |
| CAS | 5619-04-5 |
| EINECS | 227-047-1 |
| InChI | InChI=1/C4H9NO3.ClH/c1-8-4(7)3(5)2-6;/h3,6H,2,5H2,1H3;1H/t3-;/m1./s1 |
| InChIKey | NDBQJIBNNUJNHA-UHFFFAOYSA-N |
(2R)-3-hydroxy-1-methoxy-1-oxopropan-2-aminium chloride - Physico-chemical Properties
| Molecular Formula | C4H10ClNO3 |
| Molar Mass | 155.58 |
| Density | 1.37g/cm3 at 20℃ |
| Melting Point | 134-136°C(lit.) |
| Boling Point | 234.7°C at 760 mmHg |
| Flash Point | 95.8°C |
| Solubility | Methanol, Water |
| Vapor Presure | 0.00953mmHg at 25°C |
| Appearance | White crystal |
| Color | White to Off-White |
| BRN | 6067970 |
| Storage Condition | -20°C |
| Sensitive | Moisture Sensitive |
| MDL | MFCD00012593 |
(2R)-3-hydroxy-1-methoxy-1-oxopropan-2-aminium chloride - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29225000 |
(2R)-3-hydroxy-1-methoxy-1-oxopropan-2-aminium chloride - Reference Information
| LogP | -2 at 20℃ and pH7 |
| surface tension | 76mN/m at 1g/L and 20 ℃ |
| Use | DL-serine methyl ester hydrochloride as a reactant for the preparation of cichoric acid analogs as HIV-1 integrase inhibitors. It is also used for the total synthesis of (-)-benzoazole A. DL-serine methyl ester hydrochloride is an organic intermediate useful as a key intermediate in the preparation of Ramipril. |
| preparation | 30ml of methanol was added to a ML three-mouth bottle, and the mixture was mechanically stirred in an ice water bath, slowly, 5.4 of dichlorosulfoxide was added dropwise. After completion of the addition, stirring was continued for 1H, and 6.00g(57mmol) of DL-serine (II) was placed in a three-necked flask and heated to reflux for reaction, after a reaction time of 20h, the solvent was distilled off under reduced pressure and dried to give 8.28g (yield 93.7%) of DL-serine methyl ester hydrochloride. |
Last Update：2024-04-09 20:52:54
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Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: DL-Serine methyl ester hydrochloride Visit Supplier Webpage Request for quotationCAS: 5619-04-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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